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Volume 1 Issue 3
Management of Hepatitis B Virus Infection Using CRISPR/Cas Technology
HBV (hepatitis B virus) infection is a major cause of mortality and morbidity, particularly in Asia and Africa. One of the main issues in present drugs for management of hepatitis B virus infection is that, although inhibitors can inhibit the formation of viral DNA from pre-RNA transcripts but the translation and transcription of viral mRNAs from the cccDNA template do not stop by these inhibitors which are present in the nucleus of infected cell [..] READ MORE
Preferential Eradication of Gram-Negative Bacteria Using Peptide Surrogates
Short surrogates of the pentapeptide K-A-A-A-K, centered on Freidinger’s lactam, were applied in the eradication of E. Coli (Gram-negative bacteria) and S. Aureus (Gram-positive microbe). It was found that it was easier to eradicate the gram-positive bacteria, and the eradication was influenced by the N-methylation of the amide nitrogen of 30g31 (table). However, The N-methylated surrogates were more efficient in the eradi [..] READ MORE
Combatting Antimicrobial Resistance Losing the Antibiotic Umbrella?
WHO Report
Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. [..] READ MORE
Nematicidal Activity of Camellia Sinensis (Green Tea) Ethyl Alcohol Crude Extract
The nematicidal effect of ethyl alcohol extract of Camellia sinensis (Green tea) leaves were tested against Helicotylenchus indicus, Xiphinema americanum and Xiphinema index at the concentrations of 1.0 and 0.1%, extract was used in distill water and observation taken at different time periods and compared with chemical neamticide carbofuran. [..] READ MORE
Preference and Performance of the Tomato Leafminer, Tuta absoluta (Lepidoptera - Gelechiidae) Towards Three Solanaceous Host Plant Species
The tomato leaf-miner, Tuta absoluta Meyrick (Lepidoptera - Gelechiidae), is a widespread insect develops on many important solanaceous crops. The preference and performance of its host range could help in understanding and preventing the dispersion behavior of this pest in the environment. [..] READ MORE
Annihilation, Exacerbation, Prematurity: Necrotizing Enterocolitis
Necrotising enterocolitis is an intestinal inflammatory disorder predominantly affecting the preterm. The deterioration ranges from minimal mucosal trauma to pervasive necrosis of the bowel wall with perforation. [..] READ MORE
Total Articles Published
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