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Volume 8 Issue 1
Revisiting What Might Save Life of Cancer Patients Actually
Cancer patients 5-years survival chance (5YSC) is still after a Century research and development (R&D)do not changed significantly, as infectious diseases did. How Medici might increase 5YSC is not elucidated yet.
Recently I introduced death triangle machinery (DTM), which might play pivotal role in accelerating 5YSC toward increased morbidity and mortality rate in the last years [1]. [..] READ MORE
Key Problems in the Translation of Extracellular Vesicles Derived from Eukaryotic Prokaryotic Cells
Both eukaryotic and prokaryotic cells secrete extracellular vesicles (EVs). To meet the requirements of clinical application, the facile EVs were also prepared by various physical, chemical and biological methods to mimic the natural ones. Although some EVs have been at the phases of clinical trials, there are lots of challenges facing the clinical application of EVs. [..] READ MORE
Why We Still Cannot Answer Clearly If Low-Intensity Pulsed Ultrasound Treatment Can Repair Articular Cartilage?
Five years ago a question was raised. Is it possible for Low-intensity pulsed ultrasound treatment (LIPUS) to repair articular cartilage? A daily 20-minute treatment for 3 months was given to surgically created cartilage defects of 5mm in diameter on the right side distal femoral condyle of rabbits. The ultrasonic device used was an Exogen low-intensity pulsed ultrasound device (Smith & Nephew Inc, Memphis, TN, USA) which provided a peak intensity of 30mW/cm2 at a frequency of 1.5MHz. [..] READ MORE
Biomechanics Analysis of Duodenum, Jejunum and Colon of Dogs’ Cadavers
Background
Various are the alternative methods that look for the animal’s welfare in the veterinary surgery teaching, which aim to substitute the use of live animals and causing similar or superior learning to the students. [..] READ MORE
The Emerging Role of Liquid Biopsy in Oncology
The cornerstone of oncology treatment begins with the pathological diagnosis. We need tissue from the growth to have a proper diagnosis, this is achieved by an open or a needle biospy. The tissue thus obtained is subjected to various studies to help us offer the best treatment to the patient. [..] READ MORE
The Potential and Uniqueness of Fluorine in the Field of Medicinal Chemistry
The highly electronegative and unique fluorine incorporated to organic compounds can play an essential role in medicinal chemistry. The rational introduction of fluorine has the potential to modulate pKa, potency, membrane permeability and influence conformation, protein binding and pharmacokinetic properties. [..] READ MORE
Total Articles Published
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