In 2011, Hanahan and Weinberg presented the next generation of hallmarks of cancer, by providing an update of their initial review [1,2]. Deregulation of cellular energetics and evasion of immune destruction were proposed as emerging cancer hallmarks [2]. Currently, accumulating data support the reprogramming of energy metabolism as a cardinal event in carcinogenesis and sustainable cancer cell survival. [..] READ MORE
Background
WhatsApp Messenger is a popular and free messaging service providing instantaneous distribution and sharing of written, audio and video materials within a predefined group independent of location. This paper reviews the benefits and limitation of using these facilities of WhatsApp within undergraduate nursing education. [..] READ MORE
A study was conducted on 60 students (30 male and 30 female) in a Cantonment School of Bangladesh for observing their vision status. Result showed that out of 60 students myopia was the highest in male 83.33% and in female this was 53.33%. Anisometropia was the highest in female 36.67% and in male 16.67%. Hyperopia, amblyopia, and antimetropia were not found in male but in female. [..] READ MORE
Stem cell and cell derived products are included under the category of drug nowadays, as it is involve in treatment of several untreatable diseases. Therefore, in current era of modern medicine the stem cells need to pass through Food and Drug Administration (FDA) regulation of clinical trials to pass as a drug. International Society for Stem Cell Research (ISSCR) regulates clinical trials involved in stem cell research and its prospective human application. [..] READ MORE
Supply chain management of vaccine is a crucial part in national immunization program. The vaccines used during this program should have to pass global standards for safety, efficacy and quality. To define these global standards the World Health Organization (WHO) vaccines prequalification programme was started in 1987 [1]. [..] READ MORE
Background
Admission in intensive care unit is frequent for patient presenting non-variceal upper gastrointestinal bleeding (NVUGIB). To determine prognosis of those NVUGIB, prognostic scores should be used, but they are not always available at admission. The shock index (SI) is calculated from systolic blood pressure (SBP) and heart rate (HR) could more easily assess morbidity and mortality, especially, when biological and endoscopic data are hardly available like for Malagasy patien [..] READ MORE
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