Volume 3  Issue 2

The Mystery in Mother’s Blood: An Early Look to the Genetic Inheritance of Fetus

Ebru Dündar Yenilmez*, Mustafa M. Alparslan & Abdullah Tuli

The discovery of cell free fetal DNA (cffDNA) in the maternal circulation have opened up new possibilities for noninvasive prenatal diagnosis (NIPD) more than one decade. Analysis of cffDNA from maternal plasma by PCR based technologies and high resolution melting analysis (HRM) offers great potential screening single gene disorders for NIPD. The aim of our study is to screen the paternal alleles derived from father in cffDNA for the risk of alpha and beta thalassemias using HRM assay using cffD [...] READ MORE

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