Pulmonary Alveolar Microlithiasis Associated with Antiphospholipid Antibody Syndrome: A Case Report from Egypt

Abdelaziz Asmaa1, Mohamed Eman1*, Eltoukhy Hanan1, Abouelnour Amal2, Ali Amany1 & Salama Adela1

1Al-Azhar University, Faculty of Medicine, Internal Medicine, Egypt
2Al-Azhar University, Faculty of Medicine, Diagnostic Imaging, Egypt

Dr. Mohamed Eman, Al-Azhar University, Faculty of Medicine, Internal Medicine, Egypt.

Keywords: Pulmonary Alveolar Microlithiasis; A Case Report; Antiphospholipid Syndrome


Pulmonary alveolar microlithiasis (PAM) is a rare disease characterized by the presence of small calculi in the alveolar space. The authors report a case of a 55-year-old woman presented with acute left sided weakness with history of repeated abortion and previous stroke. Physical examination showed left sided hemiparesis and semihypothesia and UMNL facial paralysis. Auscultation of the chest showed Equal air entry, vesicular breathing, inspiratory fine crackling crepitations on lower left lung zone. Laboratory tests confirmed the diagnosis of antiphospholipid antibody syndrome (APS). Chest radiograph was done as routine investigation and revealed Diffuse, discrete, very small, symmetric micronodular calcifications. High-resolution CT scan revealed crazy paving pattern, calcified interlobular septa, small subpleural cysts, ground glass opacities which confirmed the diagnosis of pulmonary alveolar microlithiasis.

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