Vitamin C and Osteoarthritis: Mini Review and Commentary

Ray Marks

Department of Health, Physical Education, Gerontological Studies and Services, School of Health Sciences and Professional Studies, City University of New York, York College, NY 11451, United States and Department of Health and Behavior Studies, Teachers College, Columbia University, NY 10027, United States

Ray Marks, Department of Health and Behavior Studies, Teachers College, Columbia University, Box 114, 525W, 120th Street, New York, NY 10027, United States.

Keywords: Articular Cartilage; Ascorbic Acid; Collagen; Osteoarthritis; Vitamin C

Abstract

Osteoarthritis, the most prevalent musculoskeletal disease remains relatively impervious to successful treatment.   Moreover, available treatments may not be indicated, or efficacious, and even if they are can prove toxic and commonly fail to impact the disease directly. Vitamin C or ascorbic acid, a well-established anti-oxidant with biological proven tissue based impacts, is generally considered to have little viable impact in the broad picture of this disease. We present some data on this topic that argue for more focus on the anabolic and catabolic potential of this compound in the context of osteoarthritis. Its role in symptom management is also discussed.

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