A Case Report of Kikuchi-Fujimoto Disease in a Young Iranian Woman and Review of the Literature

Masoumi, M.^1,2*, Amirkanian, F.¹, Baghban, M.¹, Tabaraei, R.¹, Salevati Pour, A.¹ & Mullabashi, T.¹

¹Qom University of Medical Sciences (QUMS), Shahid Beheshti Hospital, Qom, Iran
²Rheumatology Research Center (RRC), Tehran University of Medical Science, Shariati Hospital, Tehran, Iran

Masoumi, M., Qom University of Medical Sciences (QUMS) and Rheumatology Research Center (RRC), Iran.

Keywords: Immunophenotype; Etiopathogenesis; Hematoxylin; Corticosteroid therapy

Abstract

Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare, benign, generally self-limiting disease first described in 1972. KFD generally affects Asian women between the ages of 20 and 35 years old. It frequently manifests as an acute or subacute form with painful posterior cervical lymphadenopathy and systemic symptoms like fever, fatigue, and headache [1-4]. More rarely, patients with KFD can also present with leukopenia, hepatosplenomegaly and complaints of fatigue, rash, arthralgia and weight loss [5].

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