Autoimmune Thyroid Disease in Patients with Polycystic Ovary Syndrome: The Role of Sexual Hormones

Mailson Batista Fernandes^1* & Aljerry Dias do Rêgo^1,2

¹Faculty of Medicine, Federal University of Amapá, Amapá, Brazil
²Department of Gynecology, Faculty of Medicine, Federal University of Amapá, Amapá, Brazil

Dr. Mailson Batista Fernandes, Faculty of Medicine, Federal University of Amapá, Amapá, Brazil.

Keywords: Polycystic Ovary Syndrome; Autoimmunity; Autoimmune; Thyroiditis; Hypothyroidism

Abstract

Introduction
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women in the menacme and involves complex pathophysiology, with genetic, metabolic and hormonal factors acting synergistically. Its endocrine-metabolic characteristics have been related to changes in thyroid physiology. PCOS and autoimmune/hormonal thyroid disease are disorders related to increased cardiovascular morbidity and mortality, making it necessary to assess the prevalence of thyroid dysfunction in PCOS patients; and what pathophysiological mechanisms of this, especially related to sexual hormones, can favor the appearance and progression of that one.
Methods
It is a review of scientific articles, searched in the MEDLINE database, through PUBMED, published in English between January 2010 and April 2018.

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