Sensitivity Pattern of Staphylococcus aureus and Escherichia coli Against Cefaclor and Cefixime

Samiyah Tasleem^1*, Sana Shamim² & Syed Baqir Naqvi²

¹Department of Microbiology, University of Karachi, Federal Urdu University of Arts, Science & Technology, Karachi, Pakistan
²Department of Pharmaceutics, Faculty of Pharmacy, University of Karachi, Pakistan

Dr. Samiyah Tasleem, Department of Microbiology, University of Karachi, Federal Urdu University of Arts, Science & Technology, Karachi, Pakistan.

Keywords: Human Pathogen; Bacterial Infection; Anti-infection Agents

Abstract

Staphylococcus aureus and Escherichia coli are associated with variety of infections in our country. The developing resistance among these organisms against different antibiotics is a serious problem all over the world. Staphylococcus aureus is a major cause of hospital - acquired infections of surgical wounds and an infection associated with medical device Escherichia coli is opportunistic pathogens it is the most common cause of urinary infections, neonatal meningitis and diarrhoea.
During the present study 50 isolates of Staphylococcus aureus and 50 isolates of Escherichia coli has been collected from the different labs, of Karachi. The sensitivity pattern of these isolates was determined against cefixime and cefaclor using disc diffusion method and data was analyzed by using National Committee for Clinical Laboratory Standard (NCCLS).

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