Bone Diseases Utilization of Bisphosphonates as Therapeutic Agents

Chika Mbah, J.

Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria

Dr. Chika Mbah, J., Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.

Keywords: Bone Diseases and the Types; Disease Management

Abstract

The human body is composed of hard tissue (bones) and soft tissues. Bones are living growing tissues which constantly go through a cycle of renewal. When bone strength and flexibility are affected by certain conditions bone diseases could develop. They are different types of bone diseases including osteoporosis, Paget’s disease, osteogenesis imperfect etc. Treatment of bone diseases may involve physical therapy, surgery, lifestyle measures and pharmacologic therapy. With pharmacologic therapy, bisphosphonates have demonstrated good efficacy and tolerability in the management of post-menopausal osteoporosis and other different skeletal disorders. In the present article, attempts will be made to present bone diseases and the types; management of the disorders including the use of bisphosphonates as the therapeutic agents of choice.

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