Systematic Review Protocol: Main Clinical Variables for the COVID-19 Patients’ Management at the Comprehensive Health Care in Brazil

Estael Luzia Coelho da Cruz-Cazarim1, Pâmela Santos Azevedo2, Adrielle Pereira Cordeiro3, Maiara Silva Araújo3, Damaris Salgueiro da Silva3, Matheus José Novais Landim3, Bárbara Caneschi da Costa3, Isadora Alhadas Oliveira Gomes3, Ana Karolina Toledo Fagundes3, Altacílio Aparecido Nunes4, Marina Morgado Garcia2, Marcelo da Silva Silvério5, Alessandra Ésther de Mendonça5 & Maurilio de Souza Cazarim5*

1School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Brazil
2School of Pharmacy, Federal University of Minas Gerais, Brazil
3School of Pharmacy, Federal University of Juiz de Fora, Brazil
4Department of Social Medicine of Ribeirão Preto Medical School, University of Sao Paulo, Brazil
5Department of Pharmaceutical Sciences, School of Pharmacy, Federal University of Juiz de Fora, Brazil

Dr. Maurilio de Souza Cazarim, Department of Pharmaceutical Sciences, School of Pharmacy; Federal University of Juiz de Fora, Brazil.

Keywords: COVID-19; Patient Management; Palliative Treatment


The epidemiological reach of COVID-19, emerging pandemic disease, has aroused concern among stakeholders worldwide about patients’ management. Understanding the factors that influence the management of the disease, which have not yet been fully elucidated, and understanding their associations in the planning actions to cope with disease. The aim was developed a systematic review protocol for answer the question: What clinical variables are correlated to the clinical management of COVID-19 in primary, specialized and hospital care? This is a systematic review protocol which has followed the Cochrane guidelines for systematic review. This protocol showed a robust method to performed a systematic review about the identification of clinical variables that are associated to progression of COVID-19. The systematic review results can aid to improve the management of COVID19 patients at the comprehensive care in Brazil.

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