Rare Atypical Presentation of Acute Hepatitis A in Children: Single Center Experience

Elsayed Ibrahim Salama

Hamad Medical Corporation and Weill Cornell Medicine, Doha, Qatar

Dr. Elsayed Ibrahim Salama, Hamad Medical Corporation and Weill Cornell Medicine, Doha, Qatar.

Keywords: Hepatitis A; HAV; Ascites; Pleural Effusion; Children

Abstract

Retrospective study from the beginning for two years at National Liver Institute, Menoufyia University, out of 20 patients with HAV were admitted, eleven of them were HAV infection associated with ascites. Inclusion criteria were: HAV-IgM +ve, no hepatic or any other chronic illness before, normal growth and nutritional status, no history of HAV vaccination. Exclusion criteria were: combined HAV infection, nephrotic syndrome, protein-losing enteropathy, malnutrition, history of filariasis and pre-existing liver cirrhosis (e.g. due to schistosomiasis). Laboratory profile of HAV (IgG, IgM), HEV, HCV-Ab, HBsAg and HBcAb (IgG, IgM) were tested by ELISA (enzyme-linked immuno-sorbent assay) via COBAS INTEGRA 400 - Roche- Diagnostics, to confirm that the child is free from other viral hepatitis.

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