Antibacterial Activities of Widely Spread Taraxacum Officinale Dandelion in Al-Qadmous, Syria as Potential Therapeutic Strategy for Antibiotic Resistant Bacteria
Rim Harfouch, M.1*, Manal Darwish2, Soumya Ghosh3, Ranim Ahmad2, Rasha Kherbeik2, Nermin Khateb2 & Conrad Chibunna Achilonu3
1Department of Microbiology and Biochemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syri
2Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syria
3Department of Genetics, Faculty of Natural & Agricultural Sciences, University of the Free State, P.O. BOX 339, Bloemfontein 9300, Free State, Republic of South Africa
Dr. Rim Harfouch, M., Department of Microbiology and Biochemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syria.
Keywords: Antibacterial Activity; Taraxacum officinale; Ethanolic Extract; Bacterial Stains; Antibiotics; Antibiotic Resistant
Medicinal plants perform an important role within the treatment of upper respiratory illness such as sore throat, cold and flu. The study aimed to highlight the biological significance of antimicrobial activities exhibited by the ethanolic extract of Taraxacum officinale (dandelion) leaves and roots against the bacterial strains. The leaves and roots of T. officinale where collected from Qadmous area, Tartous, Syria, and were extracted with ethanol and tested for their antimicrobial activities against the bacterial strains of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and the pathogenic strain of Streptococcus pneumonia along with trimethoprim/sulfamethoxazole (TMP/SMX) antibiotics (positive control). The root extracts exhibited the maximum inhibition against S. aureus, P. aeruginosa and E. coli with zone of inhibitions measuring 24mm, 17mm and 12mm respectively, in comparison to the leaves extracts that exhibited antibacterial activities against S. pneumonia (11mm) and P. aeruginosa (14mm). Notably, TMP/SMX antibiotics were observed to have larger antibacterial activities against E. coli (31mm) and S. aureus (30mm). These findings stem the possibility of using the extracts of T. officinale, especially the root extract as a co-factor to antibiotics in order to eliminate multiple antibiotics resistant bacteria, especially P. aeruginosa and S. aureus.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).