Histological and Immunohistological Studies in Patients With Transsphincteric Fistulas After Sphincter-Preserving Operations: Could Done the Data Obtained Indicate Possible Causes of Relapse of the Disease?

Kryvoruchko, I. A.^* & Firsyk, T. M.

Department of Surgery No2, Kharkiv National Medical University, Kharkiv, Ukraine

Dr. Kryvoruchko, I. A., Department of Surgery No2, Kharkiv National Medical University, Kharkiv, Ukraine.

Keywords: Rectal Fistula; Cytokines; Collagen; Investigations of Tissues; Surgery

Abstract

Background
Modern surgical approaches to the treatment of anal fistulas involve operations that least damage the sphincter complex of the rectum. The essence of the operation is a complete excision of the anal fistula, which is often accompanied by a significant number of recurrences depending on the chosen method of operation. Failure is likely the result of inflammation that persists after surgery, and cytokines play an important role in these processes.
Methods
The tissues of the fistula tract was obtained in 63 patients of both sexes with transsphincteric fistulas in 2018- 2020.

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