Anthracycline-Based Combination Chemotherapy (Doxorubicin and Dacarbazine) For the Desmoid Tumor in a Neoadjuvant Setting. Report of a Case

Divyanshu Dua* & Mahmood Shahid

Department of Medical Oncology, The Canberra Hospital, Australian National University, Australia

Dr. Divyanshu Dua, Department of Medical Oncology, The Canberra Hospital, Australian National University, Australia.

Keywords: Chemotherapy; Desmoid Tumors; Ultrasound


We report a case of a 41-year-old female with a sporadic abdominal wall desmoid tumor. After a period of 12-month observation, chemotherapy was given with Doxorubicin and Dacarbazine to facilitate minimal surgery. The patient received 4 cycles of chemotherapy. Treatment was well tolerated and resulted in a significant reduction of the tumor size from 48mm to 25mm, 48% reduction. The tumor was surgically resected, and the histopathology from the resected specimen revealed a partial pathological response. At 6 months post-surgery, there is no recurrence or surgical complications.

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