Visualization of an Intra-Operative X-Ray Source With Liquid Scintillation Imaging

Peter A. Sandwall

Department of Radiation Oncology, OhioHealth - Mansfield , OH, USA

Dr. Peter A. Sandwall,
Department of Radiation Oncology, OhioHealth - Mansfield, Ohio, USA.

Keywords: Luminescence; Scintillation; Dosimetry; Intraoperative Radiotherapy


Intraoperative radiotherapy (IORT) is an alternative to full course radiotherapy for select patients. The IntraBeam (Zeiss, Germany) delivery system uses a low energy (50kVp) x-ray source. In this communication, a method for rapidly characterizing emissions from an IORT x-ray source is shared. A leaded glass phantom was filled with liquid scintillation cocktail (LSC) (Ultima Gold; PerkinElmer, USA) and a 13 MP CMOS detector used to collect images and videos. Scintillation images were analyzed with relative intensity plotted as a function of distance from the bare probe tip. RGB channels were separated, blue selected, smoothed, and overlaid with isodose lines. Videos allowed time-resolved visualization of energy deposition. Elemental composition of LSC fluid was compared to water and soft tissue. LSC has a lower effective Z (5.9) than water (7.2) and tissue (7.1). Observed relative intensity compared to Monte Carlo depth dose in water revealed an under-response (max, 9.49% at 5mm). Optimization of LSC composition, parameters for image collection, and derivation of correction factors are areas of future study. This visualization method shows potential for rapid commissioning of an IORT x-ray source with scintillation imaging.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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