Microbiota and Pancreatic Ductal Cancer

Robert Memba^*, Laia Estalella, Erik Llàcer, Jordi Vadillo & Rosa Jorba

Hepatobiliary and Pancreatic Surgery Unit, General Surgery Department, Joan XXIII, University Hospital, Tarragona, Spain

Robert Memba, Hepatobiliary and Pancreatic Surgery Unit, General Surgery Department, Joan XXIII, University Hospital, Tarragona, Spain.

Keywords: Microbiota; Pancreatic Cancer; Microbiome; Dysbiosis

Abstract

The most common malignancy of exocrine pancreas is pancreatic ductal cancer (PDC). PDC is one of the most aggressive cancers. For the majority of patients, it remains a lethal disease, and is the 4^th leading cause of cancer death in Europe. There is no effective screening diagnostic test and most patients have advanced disease at presentation, therefore the lack of biomarkers for early detection contributes to poor outcomes. Identification of modifiable risk factors and an effective primary prevention strategy could become critical to reducing the aggressiveness of this malignancy.

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