Anti-Bacterial Activity and Phytochemical Screening of Moringa oleifera Leaves

Ghada M. A.¹, Eman Ali, N.², Howeida Mustafa, A.^3*, Nosiba Khalid⁴, Nasra Imad⁴, Namariq Izzeldeen⁴, Nazik Musa⁴, Osama Elhag, A. O.¹ & Sulieman Nasir, A. G.¹

¹Faculty of Science and Technology Omdurman Islamic University, Sudan
²Faculty of Chemical and Natural Resources Engineering, University of Iraq
³Faculty of Veterinary Medicine, University of Khartoum, Sudan
⁴Faculty of Pharmacy, Omdurman Islamic University, Sudan

Dr. Howeida Mustafa, A., Faculty of Veterinary Medicine, University of Khartoum, Sudan.

Keywords: Anti-Bacterial Medicine; Moringa Oleifera; B. Cereus; S. Arous; E. Coli; P. Aeruginosa

Abstract

Plants have been used as medicine throughout history. Medicinal plants are widely and successfully used all over the world. Moringa oleifera is one of these plants which has been found useful in nutrition, agriculture, soil control, water purification, industrial applications, cattle feed and also for treating various types of diseases in humans and livestock. In this study, the antibacterial activity of Moringa oleifera leaves anti-bacterial activity was investigated. The bioactive compounds from Moringa oleifera leaves were extracted by different solvents (Petroleum Ether, Chloroform, Methanol, Ethanol and water). The Phytochemical screening tests showed that the Moringa oleifera leaves contained; tannins, alkaloids, flavonoids, anthraquinones, glycosides, triterpenes, saponin, and cummarins. The extracts were applied to different bacterial cultures (Bacillus cereus (B. Cereus), Staphylococcus aureus (S. Arous), Escherichia coli (E. Coli), and Pseudomonas aeruginosa (P. Aeruginosa). The Moringa oleifera extracts revealed efficient anti-bacterial activity which was almost twice the anti-bacterial activity of the standard drug Gentamycin. Based on the findings of this study, it can be concluded that Moringa oleifera is a promising antibacterial agent. This confirms its efficiency as an antibacterial traditional medicine.

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