Anesthetic Control in Patients With Hyperhomocysteinemia in Eye Surgery

Diego Fajardo Puig1* & David Bolado López de Andújar2

1Department of Biochemistry and Molecular Biology, School of Medicine, Universidad Complutense de Madrid, Spain
2Hospital Universitario 12 de Octubre, School of Medicine, Universidad Complutense de Madrid, Spain

Dr. Diego Fajardo Puig & Dr. David Bolado López de Andújar, Department of Biochemistry and Molecular Biology & Hospital Universitario 12 de Octubre School of Medicine, Universidad Complutense de Madrid, Spain.

Keywords: Anesthesia; Hyperhomocysteinemia; Thromboembolism; Ectopia Lentis


Hyperhomocysteinemia is a metabolic situation in which the patient has plasma homocysteine levels higher than 12μmol/L. This fact is a risk to patient’s health because it increases the proatherothrombotic and platelet aggregation mechanisms, being a problem for the patient in a basal situation and even more, when some surgical intervention must be performed. When undergoing a surgical process to a patient with a metabolic disease that presents hyperhomocysteinemia, a special surgical algorithm must be considered to minimize the risks of developing intraoperative or postoperative thromboembolism. Patients affected by homocystinuria have a very high risk of developing a certain blindness because of the disfunction of the lens. Due to that, this review develops how the anesthetic protocol must be done in this specific type of surgical process.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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