Anesthetic Control in Patients With Hyperhomocysteinemia in Eye Surgery

Diego Fajardo Puig^1* & David Bolado López de Andújar²

¹Department of Biochemistry and Molecular Biology, School of Medicine, Universidad Complutense de Madrid, Spain
²Hospital Universitario 12 de Octubre, School of Medicine, Universidad Complutense de Madrid, Spain

Dr. Diego Fajardo Puig & Dr. David Bolado López de Andújar, Department of Biochemistry and Molecular Biology & Hospital Universitario 12 de Octubre School of Medicine, Universidad Complutense de Madrid, Spain.

Keywords: Anesthesia; Hyperhomocysteinemia; Thromboembolism; Ectopia Lentis

Abstract

Hyperhomocysteinemia is a metabolic situation in which the patient has plasma homocysteine levels higher than 12μmol/L. This fact is a risk to patient’s health because it increases the proatherothrombotic and platelet aggregation mechanisms, being a problem for the patient in a basal situation and even more, when some surgical intervention must be performed. When undergoing a surgical process to a patient with a metabolic disease that presents hyperhomocysteinemia, a special surgical algorithm must be considered to minimize the risks of developing intraoperative or postoperative thromboembolism. Patients affected by homocystinuria have a very high risk of developing a certain blindness because of the disfunction of the lens. Due to that, this review develops how the anesthetic protocol must be done in this specific type of surgical process.

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