Rapidly Progressive Acute Chest Syndrome in Sickle Cell Anemia Patients in King Abdulaziz Hospital, Jeddah

Tarneem Alghamdi

Department of Emergency Medicine, King Abdulaziz Hospital, Saudi Arabia

Dr. Tarneem Alghamdi, Department of Emergency Medicine, King Abdulaziz Hospital, Saudi Arabia.

Keywords: Chest Syndrome; Sickle Cell Disease

Abstract

Introduction
Based on existing literature. State hypotheses:
One of the most common genetic disease globally is Sickle cell disease [1]. It is characterized by abnormal Hb production i.e HbS which cause RBCs to sickle and occlude small vessels [2]. The prevelance of the disease in Saudi Arabia differs by region being the highest in the Eastern provinces followed by southwestern provinces [2]. In Saudi Arabia the disease is one of the leading causes of morbidity [3] complications of sickle cell disease include Recurrent episodes of vaso-occlusion and inflammation result in progressive damage to most organs, including the brain, kidneys, lungs, bones, and cardiovascular system, which becomes apparent with increasing age [4]. The acute chest syndrome (ACS) is one of the most frequent complications of sickle cell disease [5].

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