Article


Essence of Antioxidants in Aging Science: NRF2, a True Fact

Morshedul Alam

Department of Gene Expression Regulation, Division of Aging Science, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai, Japan

Dr. Morshedul Alam, Department of Gene Expression Regulation, Division of Aging Science, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai, Japan.

Keywords: Antioxidants; Aging Science; Oxidative Stress

Abstract

Aging Science
Literally, ‘Aging’ is the term meaning the gradual declination of our life span to death. More simply, it is the term depicting the gradual changes from younger age to older age. Aging and aging associated disorders (such as diabetes, cancer, autoimmune diseases, neuronal disorders etc) are the burning question to scientists in the medical as well as life sciences. Age is the greatest risk factor for nearly every major cause of mortality in developed nations. Despite this, most biomedical research focuses on individual disease processes without much consideration for the relationships between aging and disease. The dream of cheating death has evolved into a scientific desire to extend healthy life span. Scientists and doctors are looking for ways to maximize the number of years that we live free of chronic diseases, cancer, and cognitive decline. But before we can remedy, we have to understand the cellular and molecular mechanisms that drive aging and senescence.

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