Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects 1% of the general population. It is characterised by a dysregulation of the immune system that induces persistent synovitis and systemic inflammation, and can lead to joint destruction [1]. Despite a common clinical presentation, RA displays multiple pathogenic pathways. [..] READ MORE
The established feature of the modern world is a steady growth on the prevalence of all the major psychiatric disorders. The global predictor of this trend is the psychic traumatization of childhood and chronic psychosocial stress, triggering cumulative mechanisms of neuroepigenetic and epidemic development of mental immunodeficiency.
The task of the study is to describe the dynamics of the syndrome of mental immunodeficiency (SMID) in the early psychic traumatization of children. Mental immu [..] READ MORE
Foundational Perspective: Brief Overview of Artificial Intelligence-Driven Platforms
The Big Picture of AI-Driven Technology
First progresses in artificial intelligence (AI) start with the cybernetics era. The symbolic approach through rules-based techniques evolved later to the statistical framework as a result of the breakthrough in neural network design. This approach substantially increased accuracy in natural language processin [..] READ MORE
Purpose
New advanced clinical practitioners (ACPs = nurse practitioners and physician assistants) seeking positions in pediatric primary care have been hampered by lack of clinical experience.
Methods
A 12-month postgraduate fellowship program in primary care pediatrics was initiated for new ACPs to improve their readiness for independent practice. Fellows participated in weekly team learning discussions, monthly case presentations, quality improvement activities and super [..] READ MORE
Factitious Disorder (FD) represents a rare and challenging condition in primary and secondary care. The complexity of presentation of patients who are fabricating, or exaggerating illnesses requires an interprofessional approach to identify and treat FD successfully. The current article explores the critical routes for diagnosis and management of a disorder which can lead to unnecessary medical and surgical investigations with the risk of iatrogenic side effects or life-threatening outcomes if i [..] READ MORE
Background:
Health care workers are at risk of acquiring Human Immune Deficiency Virus infections, because of occupational exposure to blood and other body fluids. Post exposure prophylaxis has been associated with an 80% of reduction in the risk of HIV infection among Health Care Workers exposed to Human Immune Deficiency Virus/Acquired Immunodeficiency syndrome on work. Studies addressing knowledge and practice about Post exposure prophylaxis are also lacking in developing countries [..] READ MORE
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