+1 249-493-6904
Volume 1 Issue 6
Phase I Clinical Trials in the Era of Immunotherapy
Immunotherapy has changed the landscape of cancer care and has become the most promising area of cancer research over the recent years. Various stakeholders anticipate a rapid-fire development of immuneoncology (IO) agents and an accelerated regulatory approval timeline has been modernized with, [..] READ MORE
Reactive Oxygen Species (ROS) in Cancer: Review Article
Background
Cancer is one of the major heterogeneous disease with high morbidity and mortality with poor prognosis. Elevated levels of reactive oxygen species (ROS), alteration in redox balance, and deregulated redox signaling are common hallmarks of cancer progression and resistance to treatment. Mitochondria contribute mainly in the generation of ROS during oxidative phosphorylation. [..] READ MORE
Alterations in Serum VEGF Levels After Endocrine Therapy in Breast Cancer
Purpose
Angiogenesis has been suggested as a potential target for anticancer treatment, either by blocking of angiogenic factors production or by blocking of endothelial cell proliferation. The effect of preoperative chemoendocrine therapy is indefinite in the regulation of angiogenic factors, but reports propose that several anticancer drugs have antiangiogenic activity. [..] READ MORE
Evolving Insights into Brain Metastases in Patients with Oncogene Mutation-Driven Non-Small Cell Lung Cancer (NSCLC)
Brain metastases (BM) frequently develop in patients with non-small cell lung cancer (NSCLC) with a higher incidence observed in patients with oncogenic driver mutations. Management strategies for BM are rapidly evolving to reflect the advancements in lung cancer biology and the recent application of novel molecular and immunotherapies in NSCLC. [..] READ MORE
The Formula of the Waste of Cholesterol Represents a New Hope for Re - RPG- HERB2 3+ Breast Cancer with Negative Waste of Cholesterol: Case Report
Introduction
The hormone - dependence of breast cancer has been established for over a century but new investigations in its knowledge have gone away introducing with the step of years. Estrogen and progesterone receptors have been standards for the guide of treatment, but recently waste of cholesterol has emerged as a new perspective for the guide of treatment. [..] READ MORE
Evaluation of Clinical Manifestations and Their Effect on the Prognosis of Lung Cancer Patients
Survival of lung cancer patients are affected by many different factors that are extremely variable for each individual. The prognosis of lung cancer primarily depends upon the tumor type, patient immunity and treatment. The objective of our study was to determine the influence of patient symptoms, laboratory findings, imaging modalities and histopathologic tumor features on the prognostic outcome of lung cancer patients. [..] READ MORE
Total Articles Published
8
9
2
