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Volume 1 Issue 5
Breast-Cancer: The Environment in Which You Grow Before Born Matters
Breast cancer is a global public health problem [1]. It is the most common cancer in American women, being the second leading cause of cancer-related death in this group. Strategies to reduce breast cancer risk should become a major priority since this could [..] READ MORE
Targeted Therapy for KRAS Mutant Non-Small Cell Lung Cancer
Approximately one third of non-small-cell lung cancer (NSCLC) cases carry activating point mutations in the KRAS oncogene. Its protein product is known as the K-Ras protein, that is a 188-amino acid protein with 21.6 kDa molecular weight. [..] READ MORE
The Role of Circulating Tumor DNA in Cancer Management
Cancer treatment has evolved dramatically over the past decade owing to a better understanding of tumor cell biology and advances in tumor tissue genotyping (TTG). As more targetable genetic mutations are discovered, [..] READ MORE
Thyroglobulin Measurement in the Washout of Fine Needle Aspirates for the Diagnosis of Suspicious Cervical Lymph Nodes
Ultrasound-guided fine-needle aspiration cytology (FNAC) for suspicious cervical lymph nodes (CLN) is the gold standard technique for the identification of metastases from differentiated thyroid carcinomas. [..] READ MORE
Non-Invasive and Minimally Invasive Diagnosis of Cancers- Current Status and Caveats
Early detection is key to the success of anti-cancer therapies. Invasive detection methods would be ill-favored in asymptomatic individuals and there is hence a need for use of non-invasive imaging technologies or minimally invasive detection of circulating tumor features in the blood for early detection of cancers. [..] READ MORE
Limitation of Dietary Lycopene and ?-Carotene in Prostate and Breast Cancer Chemoprevention Based on Their Mechanisms of Action
Lycopene and ?-carotene are common dietary carotenoids fruits and vegetables. These carotenoids have health benefits primarily due to their anti-oxidant properties. However, in cancer chemoprevention, these antioxidant carotenoids slow down cancer initiation and progression through various mechanisms independent of antioxidant effect. [..] READ MORE
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