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Volume 1 Issue 1
HMGA1-Pseudogenes: A Paradigm of Competitive Endogenous RNA Mechanism
The genome of humans has been completely decrypted and, surprisingly, protein products are encoded by just 2% of our genes. Now, the leading goal of the scientific community is to unveil the dark matter inside the other 98% of the genome. [..] READ MORE
Management of Canine Veneral Tumor in a Labrador Dog
A male Labrador dog of the age of 2 years was presented at Referral Veterinary Polyclinic with complaint of abnormal growth near prepucial region. On clinical examination cauliflowerlike, pedunculated, nodular, papillary in appearance type of tumor noted as veneral tumor was diagnosed. It was small but dispersed growth near prepuce and was causing irritation to animal during urination. Due to licking or scratching injury was present. As the tumor [..] READ MORE
Nigrospora Sphaerica Products from the Flowering Dogwood Exhibit Antitumorigenic Effects Via the Translational Regulator, Ps6 Ribosomal Protein
The utility of diverse species of endophytic fungi as a viable source for drug agents with clinical applicability for the treatment of human diseases continues to expand. In this study we examined secondary metabolites of Nigrospora sphaerica isolated from the flowering dogwood, Cornus florida L., for their anticancer properties on lung cancer and glioblastoma. [..] READ MORE
Tocotrienols in Female Reproductive Cancers: A Long Way to Go
The discovery of vitamin E was first documented in 1922 through the finding of a particular ‘antisterility Substance-X’ that was necessary for reproduction. However, the trends in the continuing studies involving vitamin E have directed the interest on vitamin E on its antioxidant properties. [..] READ MORE
Tipifarnib, a Potential Adjuvant That Unlocks Therapeutic Resistance by Normalizing Microenvironment
More than 1.5 million new cancer cases are diagnosed in US every year [1]. Unlike the normal cells that cooperate with each other to form an ecosystem within the tissue, the cancer cells break the rules by bypassing the normal proliferation, breaching the basement membrane, disseminating into circulation and finally establishing distant colonization [2]. [..] READ MORE
Anticoagulation in Surgery
We reviewed available data in the current trends in the anticoagulants use in patients undergoing surgery in addition to hypercoagulability management in patients with malignancy. There is a comparison between oral anticoagulants vs conventional methods of thrombosis prevention as warfarin vs. other methods like anti-platelet drugs like aspirin and clopidogrel. [..] READ MORE
Total Articles Published
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